Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.54 |
| ▸ | RARA | P10276 | 2/20 | 0.51 |
| ▸ | RARG | P13631 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335534 | 1.00 | RARB (0.54) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL9336889 | 0.94 | RARB (0.52) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL9333963 | 0.92 | RARB (0.56) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL9337526 | 0.91 | RARB (0.42) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL9334310 | 0.90 | RARB (0.47) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL14175167 | 0.88 | RARB (0.66) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL9333976 | 0.87 | HSD17B10 (0.50) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL14175166 | 0.86 | RARB (0.64) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL14175164 | 0.86 | RARB (0.64) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL13310852 | 0.86 | RARB (0.68) | RARBRARARARGHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328637-A | Electrooptical devices; deformation of aligned phases and supertwisted nematic applications; miscibility, solubility | HOFFMANN-LA ROCHE INC. (US) | 1994-07-12 | — | — | US | disclosed |