Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 5/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.57 |
| ▸ | CNR1 | P21554 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337423 | 0.94 | SRD5A1 (0.59) | SRD5A1SRD5A2CNR1POLBL3MBTL1 | |
| SCHEMBL8793533 | 0.93 | SRD5A1 (0.64) | SRD5A1SRD5A2CNR1POLBL3MBTL1 | |
| SCHEMBL9334540 | 0.90 | SRD5A1 (0.70) | SRD5A1SRD5A2CNR1POLBCNR2 | |
| SCHEMBL8792355 | 0.86 | SRD5A1 (0.63) | SRD5A1SRD5A2CNR1POLBL3MBTL1 | |
| SCHEMBL9337499 | 0.85 | CNR1 (0.56) | SRD5A1SRD5A2CNR1POLBL3MBTL1 | |
| SCHEMBL27303921 | 0.84 | CNR1 (0.56) | SRD5A1SRD5A2CNR1POLBL3MBTL1 | |
| SCHEMBL8794320 | 0.84 | SRD5A1 (0.81) | SRD5A1SRD5A2CNR1POLBL3MBTL1 | |
| SCHEMBL9334471 | 0.83 | SRD5A1 (0.56) | SRD5A1SRD5A2CNR1POLBL3MBTL1 | |
| SCHEMBL9334460 | 0.83 | SRD5A1 (0.72) | SRD5A1SRD5A2CNR1CNR2CYP19A1 | |
| SCHEMBL8794032 | 0.83 | SRD5A1 (0.59) | SRD5A1SRD5A2CNR1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312829-A | Testosterone 5alpha-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5212320-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| EP-0458207-A2 | Indole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |