⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037973 | 0.82 | — | — | |
| SCHEMBL1078939 | 0.79 | MEN1 (0.43) | — | |
| SCHEMBL805042 | 0.78 | — | — | |
| SCHEMBL9667721 | 0.77 | MEN1 (0.42) | — | |
| SCHEMBL2093209 | 0.76 | — | — | |
| SCHEMBL22792608 | 0.76 | — | — | |
| SCHEMBL1578634 | 0.76 | — | — | |
| SCHEMBL513694 | 0.76 | MEN1 (0.48) | — | |
| SCHEMBL2093204 | 0.76 | — | — | |
| SCHEMBL19399866 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250223278-A1 | PYRIDAZINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. | 2025-07-10 | — | — | US | disclosed |
| WO-2025125695-A2 | CHEMICAL COMPOUNDSID50000167790940 P. DOC 2025-05-07 FILING NO.:19 | MEDCHEMICA CONSULTANCY LTD (GB) | 2025-06-19 | — | — | WO | disclosed |
| CN-114948963-B | Benzolactam compounds as protein kinase inhibitors | 大冢制药株式会社 | 2025-05-27 | — | — | CN | disclosed |
| US-12240831-B2 | Pyridazinone compounds and uses thereof | EDGEWISE THERAPEUTICS, INC. (US) | 2025-03-04 | — | — | US | disclosed |
| US-20250034170-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2025-01-30 | — | — | US | disclosed |
| US-20240368136-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-11-07 | — | — | US | disclosed |
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |
| US-12012395-B2 | Pyridazinone compounds and uses thereof | EDGEWISE THERAPEUTICS, INC. (US) | 2024-06-18 | — | — | US | disclosed |
| EP-3455224-B1 | SUBSTITUTED 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRIDINE-3(2H)-ONES AND 2,5,6,7-TETRAHYDRO-3H-PYRROLO[2,1-C][1,2,4]TRIAZOL-3-ONES, AND USE THEREOF | BAYER AG (DE) | 2024-03-27 | — | — | EP | disclosed |
| US-4845106-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4820715-A | TREATING NAUSEA AND GASTRIC DISORDERS | BRISTOL-MYERS COMPANY (US) | 1989-04-11 | — | — | US | disclosed |
| US-4808624-A | ANTIEMETICS | BRISTOL-MYERS COMPANY (US) | 1989-02-28 | — | — | US | disclosed |
| US-4742060-A | 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |
| EP-0010166-B1 | N-(1,2-AZOLYL)ALKYL-CHLOROACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1982-10-27 | — | — | EP | disclosed |
| US-4256480-A | Isoxazolyl-alkyl thiocarbamates and herbicidal compositions thereof | PHILAGRO (FR) | 1981-03-17 | — | — | US | disclosed |
| US-4220581-A | OF AMIDO AMINES, SOFTENERS, FIXATIVES, COSMETICS | NL INDUSTRIES, INC. (US) | 1980-09-02 | — | — | US | disclosed |
| US-4212861-A | PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1980-07-15 | — | — | US | disclosed |
| EP-0010166-A1 | N-(1,2-Azolyl)alkyl-chloroacetanilides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-04-30 | — | — | EP | disclosed |