Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.75 |
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KRAS | P01116 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338455 | 1.00 | ABCG2 (0.75) | ABCG2MAOATNFRSF1AAURKAMAPT | |
| SCHEMBL9338192 | 0.87 | ABCG2 (0.74) | ABCG2MAOAMAPTLMNAHPGD | |
| SCHEMBL9338182 | 0.87 | ABCG2 (0.74) | ABCG2MAOAMAPTLMNAHPGD | |
| SCHEMBL9338014 | 0.86 | ABCG2 (0.55) | ABCG2MAOATNFRSF1AMAPTLMNA | |
| SCHEMBL9337989 | 0.86 | ABCG2 (0.55) | ABCG2MAOATNFRSF1AMAPTLMNA | |
| SCHEMBL9341515 | 0.85 | ABCG2 (0.53) | ABCG2MAOAMAPTLMNAKRAS | |
| SCHEMBL9341505 | 0.85 | ABCG2 (0.53) | ABCG2MAOAMAPTLMNAKRAS | |
| SCHEMBL9342653 | 0.85 | ABCG2 (0.52) | ABCG2MAOATNFRSF1AMAPTLMNA | |
| SCHEMBL9342641 | 0.85 | ABCG2 (0.52) | ABCG2MAOATNFRSF1AMAPTLMNA | |
| SCHEMBL9337780 | 0.85 | CYP1B1 (0.61) | ABCG2MAOATNFRSF1AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |