SCHEMBL9338554

SCHEMBL9338554

CSc1ccc(C(=O)C=Cc2ccccc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.74
KMT2A Q03164 6/20 0.74
LMNA P02545 5/20 0.74
MEN1 O00255 4/20 0.74
ALDH1A1 P00352 3/20 0.74
RAB9A P51151 3/20 0.74
CASP3 P42574 2/20 0.74
SENP8 Q96LD8 2/20 0.74
SENP7 Q9BQF6 2/20 0.74
SENP6 Q9GZR1 2/20 0.74
GAA P10253 1/20 0.74
NPC1 O15118 2/20 0.72
SMN1; SMN2 Q16637 2/20 0.72
NFKB1 P19838 1/20 0.72
HTT P42858 1/20 0.72
NFKB2 Q00653 1/20 0.72
RELA Q04206 1/20 0.72
CYP1B1 Q16678 8/20 0.68
MAOB P27338 3/20 0.68
TNFRSF1A P19438 2/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9338536 1.00 MAPT (0.74) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL658201 0.93 MAPT (0.74) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL658200 0.93 MAPT (0.74) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL11815663 0.91 MAPT (0.87) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL9915661 0.91 MAPT (0.87) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL11815668 0.91 MAPT (0.87) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL10497964 0.91 MAPT (0.71) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL11814865 0.91 MAPT (0.71) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL10497973 0.91 MAPT (0.71) MAPTKMT2ALMNAMEN1ALDH1A1
SCHEMBL11814867 0.91 MAPT (0.71) MAPTKMT2ALMNAMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0328668-B1 NONLINEAR OPTICAL MATERIAL NIPPON OILS & FATS CO LTD (JP) 1994-05-25 EP claimed
EP-0328668-A1 NONLINEAR OPTICAL MATERIAL NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-08-23 EP claimed
CN-114524829-B Preparation method of imidazo [2,1-b ] thiazole derivative 新疆大学 2024-04-02 CN disclosed
CN-114524829-A Preparation method of imidazo [2,1-b ] thiazole derivative 新疆大学 2022-05-24 CN disclosed
EP-0328668-B1 NONLINEAR OPTICAL MATERIAL NIPPON OILS & FATS CO LTD (JP) 1994-05-25 EP disclosed
US-5045239-A Chalcone derivative NIPPON OIL AND FATS CO., LTD. (JP) 1991-09-03 US disclosed
EP-0328668-A1 NONLINEAR OPTICAL MATERIAL NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-08-23 EP disclosed
EP-0328669-A1 CHALCONE DERIVATIVE COMPOUNDS NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-08-23 EP disclosed