Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29890941 | 1.00 | PTPN1 (0.61) | PTPN1TSHRMAPK1GRM5CES2 | |
| Phenylacetylene SCHEMBL28207264 | 0.94 | PTPN1 (0.60) | PTPN1TSHRMAPK1GRM5CES2 | |
| SCHEMBL11239236 | 0.89 | PTPN1 (0.51) | PTPN1TSHRMAPK1GRM5FFAR1 | |
| SCHEMBL11224511 | 0.86 | PTPN1 (0.49) | PTPN1TSHRMAPK1ALDH1A1 | |
| SCHEMBL11234512 | 0.85 | PTPN1 (0.48) | PTPN1TSHRMAPK1ALDH1A1 | |
| SCHEMBL10535262 | 0.83 | PTPN1 (0.57) | PTPN1TSHRMAPK1GRM5FFAR1 | |
| SCHEMBL30873473 | 0.82 | GRM5 (0.58) | PTPN1TSHRMAPK1GRM5CES2 | |
| SCHEMBL2273427 | 0.82 | TSHR (0.52) | PTPN1TSHRMAPK1GRM5CES2 | |
| SCHEMBL17729320 | 0.79 | PTPN1 (0.49) | PTPN1TSHRMAPK1GRM5CA12 | |
| SCHEMBL695156 | 0.78 | TSHR (0.48) | PTPN1TSHRMAPK1GRM5CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119395917-A | Preparation method of anti-mode polymer stabilized cholesteric liquid crystal intelligent window with low energy consumption and high privacy | 哈尔滨工业大学 | 2025-02-07 | — | — | CN | claimed |
| CN-117624520-A | Trifluoromethyl modified pyrenyl covalent organic framework material, and preparation method and application thereof | 中国石油大学(华东) | 2024-03-01 | — | — | CN | claimed |
| CN-116082390-A | Preparation method of diethyl zinc catalyzed organosilane compound | 北京理工大学 | 2023-05-09 | — | — | CN | claimed |
| CN-114874088-A | Acetylenic acid and preparation method thereof | 中国科学院上海高等研究院 | 2022-08-09 | — | — | CN | claimed |
| EP-3051946-B1 | USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2017-11-29 | — | — | EP | claimed |
| EP-2013171-B1 | PIPERIDINES AND RELATED COMPOUNDS FOR TREATMENT OF ALZHEIMER S DISEASE | MERCK SHARP & DOHME (GB) | 2013-05-15 | — | — | EP | claimed |
| EP-1599201-B1 | SELECTIVE NON-STEROIDAL GLUCOCORTICOID RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2010-04-14 | — | — | EP | claimed |
| EP-2170805-A2 | METHODS OF SYNTHESIZING CINACALCET AND SALTS THEREOF | Amgen Inc. (US) | 2010-04-07 | — | — | EP | claimed |
| EP-1664027-B1 | SUBSTITUTED 2,3-DIHYDRO-1H-ISOINDOL-1-ONE DERIVATIVES AND METHODS OF USE | AMGEN INC (US) | 2009-12-30 | — | — | EP | claimed |
| WO-2009002427-A2 | METHODS OF SYNTHESIZING CINACALCET AND SALTS THEREOF | AMGEN INC. (US) | 2008-12-31 | — | — | WO | claimed |
| EP-1664023-B1 | SUSTITUTED ISOQUINOLINE DERIVATIVES AND METHODS OF USE | AMGEN INC (US) | 2008-08-13 | — | — | EP | claimed |
| EP-1244617-B1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO MCNEIL PHARM INC (US) | 2005-02-16 | — | — | EP | claimed |
| EP-0922050-B1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2003-07-30 | — | — | EP | claimed |
| EP-1053224-B1 | BIPHENYLSULFONYL CYANAMIDES, METHOD FOR THE PRODUCTION THEREOF AND THEIR UTILIZATION AS A MEDICAMENT | AVENTIS PHARMA GMBH (DE) | 2002-08-21 | — | — | EP | claimed |
| US-20250186408-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2025-06-12 | — | — | US | disclosed |
| WO-2025034034-A1 | NOVEL COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER OR TUMORS COMPRISING SAME | 주식회사 대웅제약 | 2025-02-13 | — | — | WO | disclosed |
| CN-119395917-A | Preparation method of anti-mode polymer stabilized cholesteric liquid crystal intelligent window with low energy consumption and high privacy | 哈尔滨工业大学 | 2025-02-07 | — | — | CN | disclosed |
| EP-1274424-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001078723-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-10-25 | — | — | WO | disclosed |
| WO-1991006533-A1 | NOVEL PROCESS FOR MANUFACTURING COMPOUNDS WITH VALUABLE PHARMACOLOGICAL PROPERTIES AND NEW INTERMEDIATE PRODUCTS FOR THE MANUFACTURE OF THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250186408-A1 | TREATMENT OF PHARMACORESISTANT EPILEPSY | CNR1, CNR2, CYP2J2 | PTPN1 3657/4885TSHR 892/4885MAPK1 3257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.