Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339227 | 0.88 | PTGER4 (0.58) | PTGER4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9339029 | 0.87 | PTGER4 (0.55) | PTGER4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9334986 | 0.83 | PTGER4 (0.54) | PTGER4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9335208 | 0.83 | NPC1 (0.55) | PTGER4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9754811 | 0.83 | NPC1 (0.55) | PTGER4NPC1RAB9ASMN1; SMN2KMT2A | |
| Bromide SCHEMBL9339050 | 0.82 | PTGER4 (0.52) | PTGER4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9335068 | 0.79 | SMN1; SMN2 (0.53) | PTGER4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9334993 | 0.78 | PTGER4 (0.53) | PTGER4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9336045 | 0.78 | PTGER4 (0.55) | PTGER4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9339025 | 0.78 | PTGER4 (0.53) | PTGER4NPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533695-B1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER (US) | 1994-10-05 | — | — | EP | disclosed |
| US-5322847-A | Inhibit platelet activating factor, block leukotriene D4 receptors | PFIZER INC. (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0533695-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. | PFIZER (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991017163-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1991-11-14 | — | — | WO | disclosed |