Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 9/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.60 |
| ▸ | CDK8 | P49336 | 4/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545424 | 0.83 | PTGS1 (0.56) | PTGS1PTGS2CDK8PIM1MAP2K2 | |
| SCHEMBL9339489 | 0.82 | CA12 (0.53) | PTGS1PTGS2MAPT | |
| SCHEMBL9339338 | 0.81 | PTGS1 (0.58) | PTGS1PTGS2KDM4C | |
| SCHEMBL9339328 | 0.79 | PTGS1 (0.52) | PTGS1PTGS2CDK8PIM1MAP2K2 | |
| SCHEMBL4370948 | 0.79 | PTGS1 (0.52) | PTGS1PTGS2CDK8PIM1MAP2K2 | |
| SCHEMBL641107 | 0.79 | MAPT (0.56) | PTGS1PTGS2CDK8PIM1MAP2K2 | |
| SCHEMBL15354404 | 0.73 | HTR2A (0.54) | SLC6A4MAPT | |
| SCHEMBL12653055 | 0.73 | HTR2A (0.54) | NPSR1SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL26985043 | 0.72 | PTGS1 (0.47) | PTGS1PTGS2CDK8PIM1MAP2K2 | |
| SCHEMBL26984921 | 0.72 | PTGS1 (0.47) | PTGS1PTGS2CDK8PIM1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317265-B1 | Novel imidate insecticides | ZENECA INC (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5089623-A | Certain imidate insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-18 | — | — | US | disclosed |
| US-5070210-A | Novel ketenimines as intermediates for insecticides | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5070097-A | MITICIDES | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5064846-A | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1991-11-12 | — | — | US | disclosed |
| US-5045566-A | Phenyl or naphthyl substituted | ICI AMERICAS INC. (US) | 1991-09-03 | — | — | US | disclosed |
| US-4994473-A | For plants | ICI AMERICAS INC. (US) | 1991-02-19 | — | — | US | disclosed |
| US-4994488-A | Controlling Lepidoptera | ICI AMERICAS INC. (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0317265-A2 | Novel imidate insecticides | ZENECA INC. (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0317259-A2 | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1989-05-24 | — | — | EP | disclosed |