Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.65 |
| ▸ | CASP6 | P55212 | 3/20 | 0.55 |
| ▸ | NSD2 | O96028 | 2/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29495016 | 0.88 | NT5E (0.71) | NT5ECASP6NSD2DUSP3PTPN5 | |
| SCHEMBL27147244 | 0.88 | NT5E (0.71) | NT5ECASP6NSD2DUSP3PTPN5 | |
| SCHEMBL29677235 | 0.88 | NT5E (0.65) | NT5ECASP6NSD2DUSP3PTPN5 | |
| SCHEMBL2928135 | 0.88 | NT5E (0.65) | NT5ECASP6NSD2DUSP3PTPN5 | |
| SCHEMBL29677298 | 0.88 | NT5E (0.65) | NT5ECASP6NSD2DUSP3PTPN5 | |
| SCHEMBL3501682 | 0.86 | NT5E (0.62) | NT5ECASP6NSD2DUSP3PTPN5 | |
| SCHEMBL9776639 | 0.82 | NT5E (0.63) | NT5ECASP6NSD2DUSP3PTPN5 | |
| SCHEMBL21894602 | 0.80 | NT5E (0.65) | NT5ECASP6NSD2DUSP3PTPN5 | |
| SCHEMBL564558 | 0.80 | NT5E (0.74) | NT5ECASP6NSD2DUSP3PTPN5 | |
| SCHEMBL66310 | 0.80 | NT5E (0.74) | NT5ECASP6NSD2DUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333653-B1 | Reactive dyes, process for their preparation and their use | CIBA GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |
| US-5256773-A | Copper complexes of 4-fluoro-5-chloropyrimidin-6-yl containing ractive mondazo dyes | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| EP-0457141-A2 | Reactive dyes | BAYER AG (DE) | 1991-11-21 | — | — | EP | disclosed |
| US-4963659-A | DYEING CELLULOSE, PRINTING TEXTILES | CIBA-GEIGY CORPORATION (US) | 1990-10-16 | — | — | US | disclosed |
| EP-0333653-A2 | Reactive dyes, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1989-09-20 | — | — | EP | disclosed |
| US-4754023-A | Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member | CIBA-GEIGY CORPORATION (US) | 1988-06-28 | — | — | US | disclosed |
| EP-0144766-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |
| US-4230618-A | CELLULOSE | ICI UNITED STATES, INC. (US) | 1980-10-28 | — | — | US | disclosed |