Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340306 | 1.00 | HTT (0.46) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL10596859 | 0.96 | HTT (0.43) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9340344 | 0.91 | HTT (0.45) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9340347 | 0.91 | HTT (0.45) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9061601 | 0.89 | HTT (0.49) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9061608 | 0.89 | HTT (0.49) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9340735 | 0.89 | KMT2A (0.43) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9340732 | 0.89 | KMT2A (0.43) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL10594470 | 0.88 | HTT (0.42) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9340587 | 0.88 | HTT (0.42) | HTTKMT2ASMN1; SMN2TDP1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348677-A | Electro-optical liquid crystal display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-20 | — | — | US | disclosed |
| US-5196140-A | ELECTRO-OPTICAL LIQUID CRYSTAL DISPLAY ELEMENT | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-23 | — | — | US | disclosed |