Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23709494 | 0.90 | CPN1 (0.40) | CPN1CPB2SIGMAR1DPP7HTR2A | |
| SCHEMBL13285534 | 0.87 | CPN1 (0.38) | CPN1CPB2SIGMAR1DPP7HTR2A | |
| SCHEMBL26489011 | 0.85 | CPN1 (0.37) | CPN1CPB2SIGMAR1HTR2A | |
| SCHEMBL22193261 | 0.83 | CPN1 (0.38) | CPN1CPB2HTR2A | |
| SCHEMBL21725498 | 0.83 | CPN1 (0.38) | CPN1CPB2HTR2A | |
| SCHEMBL20998420 | 0.83 | CPN1 (0.38) | CPN1CPB2HTR2A | |
| SCHEMBL22193247 | 0.83 | CPN1 (0.38) | CPN1CPB2HTR2A | |
| SCHEMBL29332276 | 0.82 | CPN1 (0.49) | CPN1CPB2SLC6A1SLC6A11TSHR | |
| SCHEMBL29333056 | 0.82 | CPN1 (0.49) | CPN1CPB2SLC6A1SLC6A11TSHR | |
| SCHEMBL23469399 | 0.82 | CPN1 (0.37) | CPN1CPB2SIGMAR1HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600955-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-06-15 | — | — | EP | disclosed |