Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.53 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.53 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 3/20 | 0.53 |
| ▸ | APAF1 | O14727 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.52 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340352 | 1.00 | TDP1 (0.61) | TDP1MAPTABCC4CTDSP1CNR1 | |
| SCHEMBL5972677 | 0.90 | NR1I2 (0.64) | TDP1MAPTABCC4CTDSP1CNR1 | |
| SCHEMBL9682740 | 0.90 | NR1I2 (0.64) | TDP1MAPTABCC4CTDSP1CNR1 | |
| SCHEMBL9682735 | 0.90 | NR1I2 (0.64) | TDP1MAPTABCC4CTDSP1CNR1 | |
| SCHEMBL9263764 | 0.89 | TDP1 (0.62) | TDP1MAPTABCC4CTDSP1CNR1 | |
| SCHEMBL9256716 | 0.89 | TDP1 (0.62) | TDP1MAPTABCC4CTDSP1CNR1 | |
| SCHEMBL9342424 | 0.89 | TDP1 (0.63) | TDP1MAPTABCC4CTDSP1CNR1 | |
| SCHEMBL9342431 | 0.89 | TDP1 (0.63) | TDP1MAPTABCC4CTDSP1CNR1 | |
| SCHEMBL9401379 | 0.87 | TDP1 (0.50) | TDP1MAPTABCC4CTDSP1CNR1 | |
| SCHEMBL11034346 | 0.87 | TDP1 (0.70) | TDP1MAPTABCC4CTDSP1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352792-A | Bactericides | SHIONOGI & CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0467647-B1 | Thioalkylthio cephalosporin derivatives | SHIONOGI & CO (JP) | 1994-08-17 | — | — | EP | disclosed |
| EP-0594263-A1 | Thioalkylthio cephalosporin derivatives and intermediates | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| EP-0467647-A2 | Thioalkylthio cephalosporin derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |