Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2294696 | 1.00 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL11699142 | 1.00 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL28183029 | 1.00 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL2294971 | 1.00 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL27949445 | 1.00 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL2291006 | 0.98 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL13156906 | 0.98 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| Toluene SCHEMBL27679037 | 0.94 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL15896735 | 0.93 | TSHR (0.54) | NPC1RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL13156984 | 0.93 | TSHR (0.54) | NPC1RAB9ASMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294220-B1 | Photopolymerizable composition | HITACHI CHEMICAL CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5034429-A | An unsaturated monomer, a photoinitiator and a benzene derivative for providing a cured film | HITACHI CHEMICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0294220-A2 | Photopolymerizable composition | Hitachi Chemical Co., Ltd. (JP) | 1988-12-07 | — | — | EP | disclosed |