Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340961 | 1.00 | HTT (0.42) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9340965 | 1.00 | HTT (0.42) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9336788 | 0.96 | HTT (0.45) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9336759 | 0.96 | HTT (0.45) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9337211 | 0.92 | HTT (0.41) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9337198 | 0.92 | HTT (0.41) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9337190 | 0.92 | HTT (0.41) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9336667 | 0.90 | GAA (0.41) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9336653 | 0.90 | GAA (0.41) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9336657 | 0.90 | GAA (0.41) | HTTKMT2ASMN1; SMN2TDP1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348677-A | Electro-optical liquid crystal display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-20 | — | — | US | disclosed |
| US-5196140-A | ELECTRO-OPTICAL LIQUID CRYSTAL DISPLAY ELEMENT | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-23 | — | — | US | disclosed |