SCHEMBL93410

SCHEMBL93410

O=C=Nc1cc(Cl)cc(Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
TSHR P16473 2/20 0.42
HTR3E A5X5Y0 2/20 0.41
HTR3B O95264 2/20 0.41
HTR3A P46098 2/20 0.41
HTR3D Q70Z44 2/20 0.41
HTR3C Q8WXA8 2/20 0.41
CYP3A4 P08684 4/20 0.39
TRPA1 O75762 1/20 0.39
ITGB3 P05106 1/20 0.35
ITGAV P06756 1/20 0.35
TPMT P51580 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
IDO1 P14902 2/20 0.31
ERN1 O75460 1/20 0.31
SOD1 P00441 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28202222 0.97 MAPK1 (0.50) MAPK1TDP1TSHRHTR3EHTR3B
SCHEMBL10316610 0.95 MAPK1 (0.52) MAPK1TDP1TSHRHTR3EHTR3B
SCHEMBL28207334 0.89 CYP3A4 (0.54) MAPK1TDP1TSHRHTR3EHTR3B
Chlorobenzene SCHEMBL28207890 0.87 MAPK1 (0.47) MAPK1TDP1TSHRHTR3EHTR3B
SCHEMBL7921988 0.84 MAPK1 (0.44) MAPK1TDP1TSHRHTR3EHTR3B
SCHEMBL5444503 0.84 MAPK1 (0.44) MAPK1TDP1TSHRHTR3EHTR3B
SCHEMBL15935856 0.84 CYP3A4 (0.48) MAPK1TDP1TSHRHTR3EHTR3B
Toluene SCHEMBL28207248 0.82 TDP1 (0.43) MAPK1TDP1TSHRCYP3A4TRPA1
SCHEMBL28224736 0.81 MAPK1 (0.38) MAPK1TDP1
SCHEMBL131042 0.80 TDP1 (0.50) MAPK1TDP1TSHRCYP3A4TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 993 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960017-B Modified acrylic ester monomer and photo-curable resin thereof 上海华峰龙湾技术有限公司 2024-11-22 CN claimed
CN-117964892-A Modified macromer, preparation method thereof and application thereof in polymer polyol 中国石油化工股份有限公司 2024-05-03 CN claimed
CN-117945952-A Method for preparing 1-carboxymethyl-3- (3, 5-dichlorophenyl) urea 江西禾益化工股份有限公司 2024-04-30 CN claimed
CN-117327201-A Hydrophobic nanocellulose and preparation method and application thereof 中国科学院理化技术研究所 2024-01-02 CN claimed
CN-114634449-B Preparation method of 3- (3, 5-dichlorophenyl) -2, 4-imidazolidinedione 北京颖泰嘉和生物科技股份有限公司 2023-12-26 CN claimed
CN-107774199-B Dripping device and dripping method in 3, 5-dichlorophenyl isocyanate cold light process 中国平煤神马能源化工集团有限责任公司 2023-11-10 CN claimed
CN-116525948-A Method for inhibiting corrosion of aluminum foil of lithium battery current collector based on isocyanate additive 临沂大学 2023-08-01 CN claimed
CN-115960017-A Modified acrylate monomer and photocurable resin thereof 上海华峰龙湾技术有限公司 2023-04-14 CN claimed
CN-112375226-B Bonded amylose derivative and preparation method and application thereof 苏州纳微科技股份有限公司 2023-03-17 CN claimed
CN-115566271-A Organic electrolyte and lithium ion secondary battery 九江天赐高新材料有限公司 2023-01-03 CN claimed
US-20090216006-A1 COVALENTLY BOUND POLYSACCHARIDE-BASED CHIRAL STATIONARY PHASES AND METHOD FOR THEIR PREPARATION XU HUI 2009-08-27 US claimed
US-20090105440-A1 Filler for Optical Isomer Separation NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2009-04-23 US claimed
EP-2028487-A1 FILLER FOR OPTICAL ISOMER SEPARATION National University Corporation Nagoya University (JP) 2009-02-25 EP claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
CN-1209356-C Method for splitting antipode of 3-butylbenzene phthalein DALIAN CHEMICAL PHYSICS INST (CN) 2005-07-06 CN claimed
CN-1539835-A Method for splitting antipode of 3-butylbenzene phthalein 中国科学院大连化学物理研究所 2004-10-27 CN claimed
US-5679572-A A CHROMATOGRAPHY MATRIX COMPRISING A POLYSACCHARIDE BONDED TO THE INNER AND OUTER SURFACES OF A SURFACE-TREATED POROUS CARRIER DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1997-10-21 US claimed
US-4810799-A Preparation of N-(3,5-dichlorophenyl)oxazolidine-2,4-diones BASF AKTIENGESELLSCHAFT (DE) 1989-03-07 US claimed
EP-0131903-B1 PROCESS FOR THE PREPARATION OF N-(3,5-DICHLOROPHENYL)-OXAZOLIDINE-2,4-DIONES BASF Aktiengesellschaft (DE) 1988-09-28 EP claimed
EP-0131902-A2 Compositions being liquid, storage-stable, and activatable at room temperature, made from polyols and/or polyamines and polyisocyanates, for polyurethane pressure-sensitive masses BASF Aktiengesellschaft (DE) 1985-01-23 EP claimed