Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340717 | 1.00 | HTT (0.41) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9340711 | 1.00 | HTT (0.41) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9341059 | 1.00 | HTT (0.41) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9340584 | 0.99 | HTT (0.42) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9340587 | 0.99 | HTT (0.42) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9340502 | 0.97 | HTT (0.39) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9336521 | 0.97 | HTT (0.39) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9340495 | 0.97 | HTT (0.39) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9336525 | 0.97 | HTT (0.39) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9340312 | 0.95 | HTT (0.40) | HTTKMT2ASMN1; SMN2TDP1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348677-A | Electro-optical liquid crystal display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-20 | — | — | US | disclosed |
| US-5196140-A | ELECTRO-OPTICAL LIQUID CRYSTAL DISPLAY ELEMENT | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-23 | — | — | US | disclosed |