Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | PPOX | P50336 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831780 | 0.84 | MEN1 (0.60) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11116937 | 0.84 | TDP1 (0.72) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10648910 | 0.84 | TDP1 (0.66) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10499965 | 0.83 | TDP1 (0.77) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11364733 | 0.82 | TDP1 (0.72) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10786867 | 0.81 | TDP1 (0.81) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10650691 | 0.81 | TDP1 (0.64) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10655496 | 0.81 | TDP1 (0.64) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10500001 | 0.81 | MEN1 (0.73) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10791384 | 0.81 | TDP1 (0.63) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290756-A | Herbicides | ROHM AND HAAS COMPANY (US) | 1994-03-01 | — | — | US | disclosed |
| US-4877897-A | HERBICIDES | ROHM AND HAAS COMPANY (US) | 1989-10-31 | — | — | US | disclosed |