Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PPOX | P50336 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11671733 | 0.85 | TDP1 (0.64) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10784983 | 0.84 | TDP1 (0.78) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9341324 | 0.84 | TDP1 (0.77) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL30862569 | 0.83 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL8541647 | 0.83 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL38816 | 0.83 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9342535 | 0.83 | TDP1 (0.78) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9342519 | 0.83 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9347507 | 0.82 | TDP1 (0.74) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL28419037 | 0.82 | TDP1 (0.98) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304531-A | Preemergent, postemergent, controls weed growth 2-chloro-4-trifluoromethyl-3' (1-(carboethoxy) ethoxycarbonyl)-4-nitrodiphenyl ether | BASF CORPORATION | 1994-04-19 | — | — | US | disclosed |
| US-5214190-A | Nitrophenyl ether herbicides | JOHNSON WAYNE O (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0020052-A1 | Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, processes for the preparation thereof and the use thereof for combating weeds | ROHM AND HAAS COMPANY (US) | 1980-12-10 | — | — | EP | disclosed |