Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PDE6D | O43924 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1078205 | 1.00 | HMGCR (0.44) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL1738989 | 0.92 | ABCC3 (0.46) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| Zinc Ion SCHEMBL1078270 | 0.92 | ABCC3 (0.45) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL1740055 | 0.82 | HMGCR (0.41) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| Tert-Butylamine SCHEMBL1739620 | 0.80 | HMGCR (0.40) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL1739610 | 0.79 | ABCC3 (0.43) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL2684321 | 0.79 | ABCC3 (0.42) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| Zinc Ion SCHEMBL1741829 | 0.79 | ABCC3 (0.42) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL15004853 | 0.78 | HMGCR (0.70) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 | |
| SCHEMBL6427204 | 0.78 | HMGCR (0.70) | HMGCRALDH1A1CYP3A4PDE6DNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128346-A3 | ROSUVASTATIN MANGANSE, COPPER, IRON AND ZINC SALTS WITH HIGH PHOTOCHEMICAL STABILITY | EGIS GYÓGYSZERGYÁR NYILVÁNOSAN MUKODO RESZVENYTÁRSASÁG (HU) | 2011-01-13 | — | — | WO | disclosed |
| WO-2010128346-A2 | ROSUVASTATIN SALTS AND METHOD FOR PREPARATION THEREOF | EGIS GYÓGYSZERGYÁR NYILVÁNOSAN MUKODO RESZVENYTÁRSASÁG (HU) | 2010-11-11 | — | — | WO | disclosed |