Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | DUT | P33316 | 2/20 | 0.52 |
| ▸ | POLA1 | P09884 | 1/20 | 0.49 |
| ▸ | TYMP | P19971 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665070 | 0.85 | KDM4E (0.62) | KDM4EPOLA1TYMPTAS1R3TAS1R1 | |
| SCHEMBL6470562 | 0.85 | KDM4E (0.62) | KDM4EPOLA1TYMPTAS1R3TAS1R1 | |
| SCHEMBL17279165 | 0.85 | KDM4E (0.62) | KDM4EPOLA1TYMPTAS1R3TAS1R1 | |
| SCHEMBL8440176 | 0.85 | KDM4E (0.64) | KDM4EPOLA1TYMPTAS1R3TAS1R1 | |
| SCHEMBL8440184 | 0.85 | KDM4E (0.64) | KDM4EPOLA1TYMPTAS1R3TAS1R1 | |
| SCHEMBL25507075 | 0.85 | KDM4E (0.72) | KDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL264545 | 0.85 | KDM4E (0.72) | KDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL20346237 | 0.85 | KDM4E (0.72) | KDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL17676619 | 0.85 | KDM4E (0.65) | KDM4EPOLA1TYMPTAS1R3TAS1R1 | |
| SCHEMBL25504735 | 0.85 | KDM4E (0.65) | KDM4EPOLA1TYMPTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270651-B1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES | CALIFORNIA INST OF TECHN (US) | 1994-06-15 | — | — | EP | disclosed |