⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494705 | 1.00 | — | — | |
| SCHEMBL9343798 | 1.00 | — | — | |
| SCHEMBL9492889 | 1.00 | — | — | |
| Dipentylamine SCHEMBL9344094 | 0.99 | — | — | |
| SCHEMBL7108735 | 0.94 | — | — | |
| SCHEMBL7108644 | 0.94 | — | — | |
| SCHEMBL7567375 | 0.94 | — | — | |
| SCHEMBL7565223 | 0.94 | — | — | |
| SCHEMBL7566112 | 0.93 | — | — | |
| SCHEMBL7569944 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288757-A | Aminosulfonyl urea ACAT inhibitors and a method of lowering blood cholesterol levels therewith | WARNER-LAMBERT COMPANY (US) | 1994-02-22 | — | — | US | disclosed |
| US-5214206-A | Anticholesterol agents, inhibitors of acylcoenzyme A | WARNER-LAMBERT COMPANY (US) | 1993-05-25 | — | — | US | disclosed |
| WO-1992008694-A1 | AMINOSULFONYL UREA ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |