Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | TTR | P02766 | 1/20 | 0.67 |
| ▸ | PPOX | P50336 | 1/20 | 0.67 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575673 | 0.92 | TDP1 (0.70) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10822564 | 0.91 | MEN1 (0.69) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11032097 | 0.89 | MEN1 (0.67) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11114585 | 0.88 | TDP1 (0.70) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11310937 | 0.88 | MEN1 (0.48) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10908914 | 0.88 | MEN1 (0.67) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL30088466 | 0.87 | MEN1 (0.74) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL5933816 | 0.87 | MEN1 (0.74) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL38860 | 0.86 | MEN1 (0.68) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10536730 | 0.86 | MEN1 (0.67) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304531-A | Preemergent, postemergent, controls weed growth 2-chloro-4-trifluoromethyl-3' (1-(carboethoxy) ethoxycarbonyl)-4-nitrodiphenyl ether | BASF CORPORATION | 1994-04-19 | — | — | US | disclosed |
| EP-0020052-B1 | NOVEL SUBSTITUTED NITRODIPHENYL ETHERS, HERBICIDAL COMPOSITIONS CONTAINING THEM, PROCESSES FOR THE PREPARATION THEREOF AND THE USE THEREOF FOR COMBATING WEEDS | ROHM AND HAAS COMPANY (US) | 1983-07-20 | — | — | EP | disclosed |
| EP-0020052-A1 | Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, processes for the preparation thereof and the use thereof for combating weeds | ROHM AND HAAS COMPANY (US) | 1980-12-10 | — | — | EP | disclosed |