Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC12A2 | P55011 | 1/20 | 0.35 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344155 | 1.00 | SLC12A2 (0.35) | SLC12A2SLC12A5NPC1CA12CA9 | |
| SCHEMBL9348801 | 0.94 | PLA2G2C (0.35) | SLC12A2SLC12A5NPC1CA12CA9 | |
| SCHEMBL9348812 | 0.94 | PLA2G2C (0.35) | SLC12A2SLC12A5NPC1CA12CA9 | |
| SCHEMBL9345687 | 0.94 | CYP24A1 (0.35) | SLC12A2SLC12A5NPC1CA12CA9 | |
| SCHEMBL9345709 | 0.94 | CYP24A1 (0.35) | SLC12A2SLC12A5NPC1CA12CA9 | |
| SCHEMBL26837241 | 0.90 | SLC12A2 (0.36) | SLC12A2SLC12A5NPC1CA12CA9 | |
| SCHEMBL9626662 | 0.85 | SLC12A2 (0.37) | SLC12A2SLC12A5CA12CA9CA1 | |
| SCHEMBL27031979 | 0.85 | SLC12A2 (0.37) | SLC12A2SLC12A5CA12CA9CA1 | |
| SCHEMBL27130489 | 0.85 | SLC12A2 (0.37) | SLC12A2SLC12A5CA12CA9CA1 | |
| SCHEMBL27032127 | 0.85 | SLC12A2 (0.37) | SLC12A2SLC12A5CA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5275756-A | Pyrimidine ether compounds for electrooptical elements | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0469893-A1 | Fluorinated pyrimidine-phenyl optically active compounds and liquid crystal compositions thereof | Takasago International Corporation (JP) | 1992-02-05 | — | — | EP | disclosed |