Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 4/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344226 | 1.00 | NR5A1 (0.47) | NR5A1LTA4HPARP15PARP10PARP2 | |
| SCHEMBL9345672 | 1.00 | NR5A1 (0.47) | NR5A1LTA4HPARP15PARP10PARP2 | |
| SCHEMBL9349645 | 1.00 | NR5A1 (0.47) | NR5A1LTA4HPARP15PARP10PARP2 | |
| SCHEMBL9345097 | 1.00 | NR5A1 (0.47) | NR5A1LTA4HPARP15PARP10PARP2 | |
| SCHEMBL9346256 | 1.00 | NR5A1 (0.47) | NR5A1LTA4HPARP15PARP10PARP2 | |
| SCHEMBL9344417 | 1.00 | NR5A1 (0.47) | NR5A1LTA4HPARP15PARP10PARP2 | |
| SCHEMBL9349205 | 1.00 | NR5A1 (0.47) | NR5A1LTA4HPARP15PARP10PARP2 | |
| SCHEMBL9344283 | 0.98 | NR5A1 (0.46) | NR5A1LTA4HPARP15PARP10PARP2 | |
| SCHEMBL9349214 | 0.98 | NR5A1 (0.46) | NR5A1LTA4HPARP15PARP10PARP2 | |
| SCHEMBL9346047 | 0.98 | NR5A1 (0.45) | NR5A1LTA4HPARP15PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344557-B1 | Liquid crystal components with a trimethylenoxy group | HOFFMANN LA ROCHE (CH) | 1994-08-10 | — | — | EP | disclosed |
| US-5238600-A | IBIMETHYLENOXY CONTAINING LIQUID CRYSTAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0344557-A2 | Liquid crystal components with a trimethylenoxy group | F. HOFFMANN-LA ROCHE AG (CH) | 1989-12-06 | — | — | EP | disclosed |