Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344635 | 0.95 | MAPT (0.39) | MAPTCYP1A2HTTLMNAMAPK1 | |
| SCHEMBL9349619 | 0.93 | TP53 (0.39) | MAPTCYP1A2HTTLMNAMAPK1 | |
| SCHEMBL9346394 | 0.93 | TP53 (0.39) | MAPTCYP1A2HTTLMNAMAPK1 | |
| SCHEMBL9344290 | 0.93 | MAPT (0.43) | MAPTCYP1A2HTTLMNAMAPK1 | |
| SCHEMBL9345061 | 0.93 | MAPT (0.33) | MAPTCYP1A2HTTLMNAMAPK1 | |
| SCHEMBL9346574 | 0.92 | MAPT (0.42) | MAPTCYP1A2HTTLMNAMAPK1 | |
| SCHEMBL9349317 | 0.91 | MAPT (0.41) | MAPTCYP1A2HTTLMNAMAPK1 | |
| SCHEMBL9348993 | 0.91 | MAPT (0.36) | MAPTCYP1A2HTTLMNAMAPK1 | |
| SCHEMBL9345426 | 0.91 | MAPT (0.36) | MAPTCYP1A2HTTLMNAMAPK1 | |
| SCHEMBL9346340 | 0.90 | TP53 (0.40) | MAPTCYP1A2HTTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344557-B1 | Liquid crystal components with a trimethylenoxy group | HOFFMANN LA ROCHE (CH) | 1994-08-10 | — | — | EP | disclosed |
| EP-0344557-A2 | Liquid crystal components with a trimethylenoxy group | F. HOFFMANN-LA ROCHE AG (CH) | 1989-12-06 | — | — | EP | disclosed |