⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28617020 | 0.68 | — | — | |
| SCHEMBL2014272 | 0.66 | TSHR (0.31) | — | |
| SCHEMBL6323838 | 0.65 | — | — | |
| SCHEMBL7358051 | 0.62 | — | — | |
| SCHEMBL28852456 | 0.59 | — | — | |
| SCHEMBL29494651 | 0.57 | — | — | |
| Maleic Anhydride SCHEMBL27602816 | 0.57 | CA1 (0.31) | — | |
| SCHEMBL7321711 | 0.56 | — | — | |
| SCHEMBL138698 | 0.56 | — | — | |
| SCHEMBL18121363 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288752-A | Brain disorders | SUNTORY LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0322248-B1 | COMPOUNDS EFFECTIVE AGAINST CEREBRAL INSUFFICIENCY | SUNTORY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5179092-A | Cognition activators | SUNTORY LIMITED (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5057514-A | Compounds effective as cerebral schemia treating agents | SUNTORY LIMITED (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0322248-A2 | Compounds effective against cerebral insufficiency | SUNTORY LIMITED (JP) | 1989-06-28 | — | — | EP | disclosed |