Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623442 | 1.00 | MAPT (0.46) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL9344725 | 1.00 | MAPT (0.46) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL11311721 | 0.91 | POLB (0.38) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL11311725 | 0.91 | MAPT (0.39) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL8843840 | 0.91 | MAPT (0.44) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL11311717 | 0.91 | POLB (0.38) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL9021455 | 0.91 | MAPT (0.44) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL15500658 | 0.91 | MAPT (0.44) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL9344746 | 0.90 | MAPT (0.39) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL9344751 | 0.90 | MAPT (0.39) | MAPTGAALMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336776-A | Cephalopsporin intermediates; Staphyloccus septicemia and skin disorders; penicillin-resistant gramnegative bacteria | ROUSSEL UCLAF (FR) | 1994-08-09 | — | — | US | disclosed |
| US-5103012-A | Chemical intermediate | ROUSSEL UCLAF (FR) | 1992-04-07 | — | — | US | disclosed |
| EP-0238060-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS | Banyu Pharmaceutical Co., Ltd. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4988816-A | Chemical intermediates for cephalosporin antibiotics | ROUSSEL UCLAF (FR) | 1991-01-29 | — | — | US | disclosed |
| EP-0121244-B1 | CEPHALOSPORIN DERIVATIVES | Bristol-Myers Company (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4843164-A | CEPHALOSPORIN INTERMEDIATE; ANTIBIOTIC | ROUSSEL UCLAF (FR) | 1989-06-27 | — | — | US | disclosed |
| US-4814328-A | Cephalosporin derivatives, and antibacterial agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4782155-A | ISOQUINOLINE SALTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0238060-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |
| US-4576938-A | Cephalosporin compound and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1986-03-18 | — | — | US | disclosed |
| US-4525473-A | BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1985-06-25 | — | — | US | disclosed |
| EP-0121244-A2 | Cephalosporin derivatives | Bristol-Myers Company (US) | 1984-10-10 | — | — | EP | disclosed |
| US-4406899-A | Cephalosporins | BRISTOL-MYERS COMPANY (US) | 1983-09-27 | — | — | US | disclosed |
| EP-0081971-A2 | Novel cephalosporin compound and process for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1983-06-22 | — | — | EP | disclosed |
| US-4376203-A | ANTIBIOTIC | ROUSSELL UCLAF (FR) | 1983-03-08 | — | — | US | disclosed |
| US-4283396-A | 3-Acetoxymethyl-7-(hydroxyiminoacetamido)-cephalosporanic acid derivatives | ROUSSEL UCLAF (FR) | 1981-08-11 | — | — | US | disclosed |
| US-4196205-A | ANTIBIOTICS, BACTERICIDES | ROUSSEL UCLAF (FR) | 1980-04-01 | — | — | US | disclosed |
| US-4152432-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1979-05-01 | — | — | US | disclosed |