Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.76 |
| ▸ | BACE1 | P56817 | 4/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 3/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.67 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.64 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344834 | 1.00 | GSK3B (0.76) | GSK3BBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11387732 | 0.90 | GSK3B (0.66) | GSK3BBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11387734 | 0.90 | GSK3B (0.66) | GSK3BBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL527828 | 0.88 | GSK3B (0.80) | GSK3BBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7999149 | 0.88 | GSK3B (0.83) | GSK3BBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL527827 | 0.88 | GSK3B (0.80) | GSK3BBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7999153 | 0.88 | GSK3B (0.83) | GSK3BBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8740053 | 0.88 | GSK3B (0.80) | GSK3BBACE1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7054738 | 0.86 | GSK3B (0.78) | GSK3BBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2776601 | 0.85 | GSK3B (0.76) | GSK3BBACE1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450711-B1 | Substituted cyclohexanediones and their herbicidal uses | DOWELANCO (US) | 1994-07-13 | — | — | EP | disclosed |
| WO-1991015119-A1 | SUBSTITUTED CYCLOHEXANEDIONES AND THEIR HERBICIDAL USES | DOWELANCO (US) | 1991-10-17 | — | — | WO | disclosed |
| WO-1991015123-A1 | SUBSTITUTED CYCLOHEXANEDIONES AND THEIR HERBICIDAL USES | DOWELANCO (US) | 1991-10-17 | — | — | WO | disclosed |
| EP-0450711-A1 | Substituted cyclohexanediones and their herbicidal uses | DOWELANCO (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0449385-A2 | Substituted cyclohexanediones and their herbicidal uses | DOWELANCO (US) | 1991-10-02 | — | — | EP | disclosed |
| US-5006159-A | Oximes, effective against grassy weeds but selective to broadleaf crops such as cotton, sugar beets, soybeans, wheat, rice and corn | DOWELANCO (US) | 1991-04-09 | — | — | US | disclosed |
| US-4983211-A | Substituted cyclohexanediones and their herbicidal use | DOWELANCO (US) | 1991-01-08 | — | — | US | disclosed |
| US-4534979-A | Polyene compounds useful in the treatment of psoriasis and allergic responses | USV PHARMACEUTICAL CORP. (US) | 1985-08-13 | — | — | US | disclosed |
| EP-0071399-A2 | Substituted pyrrolidine cardiovascular system regulators and antihypertensives, their preparation and use | SYNTEX (U.S.A.) INC. (US) | 1983-02-09 | — | — | EP | disclosed |
| US-4262013-A | ANTILIPEMIC AGENTS | SANKYO COMPANY LIMITED (JP) | 1981-04-14 | — | — | US | disclosed |
| US-4198425-A | ANTILIPEMIC AGENTS | SANKYO COMPANY LIMITED (JP) | 1980-04-15 | — | — | US | disclosed |