Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 15/20 | 1.00 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657877 | 0.85 | AHR (0.72) | AHR | |
| SCHEMBL6466406 | 0.83 | AHR (0.68) | AHRFLT1 | |
| SCHEMBL30927171 | 0.81 | AHR (1.00) | AHRALOX15 | |
| SCHEMBL32668978 | 0.79 | AHR (1.00) | AHRFLT1ALOX15ALOX12APEX1 | |
| SCHEMBL9657329 | 0.77 | AHR (0.61) | AHRALOX15 | |
| SCHEMBL9508084 | 0.76 | AHR (0.60) | AHR | |
| SCHEMBL22032472 | 0.72 | AHR (0.55) | AHR | |
| SCHEMBL3526305 | 0.69 | AHR (0.53) | AHR | |
| SCHEMBL1751672 | 0.69 | AHR (0.53) | AHR | |
| SCHEMBL356698 | 0.69 | AHR (0.50) | AHRALOX15APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251635-B1 | Monoclonal antibodies and method for detecting dioxins and dibenzofurans | UNIV CALIFORNIA (US) | 1994-08-10 | — | — | EP | claimed |
| EP-0251635-A2 | Monoclonal antibodies and method for detecting dioxins and dibenzofurans | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1988-01-07 | — | — | EP | claimed |
| EP-0251635-B1 | Monoclonal antibodies and method for detecting dioxins and dibenzofurans | UNIV CALIFORNIA (US) | 1994-08-10 | — | — | EP | disclosed |