Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345114 | 0.95 | HRH3 (0.44) | KDM4ENFE2L2HRH3MEN1KMT2A | |
| SCHEMBL9349652 | 0.92 | HTT (0.47) | KDM4EHRH3MEN1KMT2ACYP1A2 | |
| SCHEMBL9349452 | 0.89 | HRH3 (0.52) | HRH3MEN1 | |
| SCHEMBL9348861 | 0.88 | HTT (0.43) | KDM4EHRH3MEN1KMT2A | |
| SCHEMBL9349086 | 0.87 | HPGD (0.43) | KDM4ENFE2L2HRH3MEN1KMT2A | |
| SCHEMBL9345239 | 0.87 | HRH3 (0.48) | KDM4EHRH3RECQLTDP1 | |
| SCHEMBL9589728 | 0.87 | MEN1 (0.52) | MEN1KMT2A | |
| SCHEMBL9590114 | 0.86 | MEN1 (0.36) | KDM4ENFE2L2HRH3MEN1KMT2A | |
| SCHEMBL9346382 | 0.86 | HRH3 (0.58) | HRH3 | |
| SCHEMBL9346003 | 0.86 | PARP15 (0.39) | KDM4ENFE2L2HRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344557-B1 | Liquid crystal components with a trimethylenoxy group | HOFFMANN LA ROCHE (CH) | 1994-08-10 | — | — | EP | disclosed |
| US-5238600-A | IBIMETHYLENOXY CONTAINING LIQUID CRYSTAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0344557-A2 | Liquid crystal components with a trimethylenoxy group | F. HOFFMANN-LA ROCHE AG (CH) | 1989-12-06 | — | — | EP | disclosed |