Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10618619 | 0.95 | GAA (0.44) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9340570 | 0.93 | GAA (0.47) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9342605 | 0.92 | GAA (0.41) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL132812 | 0.88 | GAA (0.51) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10915909 | 0.86 | GAA (0.44) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10915912 | 0.86 | GAA (0.44) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9345240 | 0.86 | GAA (0.33) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7245953 | 0.85 | GAA (0.43) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL29011479 | 0.85 | GAA (0.43) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9342618 | 0.85 | GAA (0.48) | GAAKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421928-B1 | Hydroxyphenylcarboxylic acid esters as stabilizers | CIBA GEIGY AG (CH) | 1994-06-15 | — | — | EP | disclosed |
| US-5177246-A | Hydroxphenylcarboxylic acid esters as stabilizers | CIBA-GEIGY CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0421928-A2 | Hydroxyphenylcarboxylic acid esters as stabilizers | CIBA-GEIGY AG (CH) | 1991-04-10 | — | — | EP | disclosed |