Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 7/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12141547 | 0.83 | MAPT (0.52) | MAPTPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL1845243 | 0.80 | MAPT (0.49) | MAPTPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL2488282 | 0.80 | MAPT (0.53) | MAPTPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL20784571 | 0.80 | MAPT (0.49) | MAPTPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL131857 | 0.80 | MAPT (0.49) | MAPTPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL487644 | 0.80 | TSHR (0.39) | GABRA1GABRA5 | |
| SCHEMBL508250 | 0.80 | MAPT (0.49) | MAPTPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL21909732 | 0.80 | MAPT (0.49) | MAPTPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL14406811 | 0.79 | MAPT (0.45) | MAPTPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL9360618 | 0.79 | ACACB (0.40) | MAPTPIK3CDPIK3CAPIK3CBPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393453-B1 | Process for the preparation of 2-chloro-5-chloromethyl-pyridine and new intermediates | BAYER AG (DE) | 1994-11-30 | — | — | EP | disclosed |
| US-5329011-A | Process for the preparation of 2-chloro-5-chloromethyl-pyridine, and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| US-5233043-A | 2-alkoxy-5-alkoxymethyl-pyridines and a process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-03 | — | — | US | disclosed |
| US-5116993-A | PROCESS FOR THE PREPARATION OF 2-CHLORO-5-CHLOROMETHYLPYRIDINE, AND NEW INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |
| EP-0393453-A2 | Process for the preparation of 2-chloro-5-chloromethyl-pyridine and new intermediates | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |