Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959228 | 0.85 | HIF1A (0.41) | FLT1FLT4KDRKCNH2SMN1; SMN2 | |
| SCHEMBL16956502 | 0.83 | KCNH2 (0.42) | FLT1FLT4KDRKCNH2SMN1; SMN2 | |
| SCHEMBL7224195 | 0.78 | FLT1 (0.46) | FLT1FLT4KDRKCNH2SMN1; SMN2 | |
| SCHEMBL9100129 | 0.77 | CNR1 (0.45) | HMGCRALOX5 | |
| SCHEMBL1069010 | 0.77 | TAAR1 (0.41) | HPGDMEN1MAPTKMT2AHTT | |
| SCHEMBL12847324 | 0.77 | KCNH2 (0.46) | FLT1FLT4KDRKCNH2SMN1; SMN2 | |
| SCHEMBL10823204 | 0.77 | FLT1 (0.45) | FLT1FLT4KDRKCNH2SMN1; SMN2 | |
| SCHEMBL19278265 | 0.77 | FLT1 (0.45) | FLT1FLT4KDRKCNH2SMN1; SMN2 | |
| SCHEMBL10823208 | 0.77 | CYP3A4 (0.45) | FLT1FLT4KDRKCNH2SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL14718591 | 0.77 | FLT1 (0.45) | FLT1FLT4KDRKCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294720-A | Viricides | THE DUPONT MERCK PHARMACEUTICAL CO. (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0089769-B1 | 9-SUBSTITUTED CARBACYCLIN ANALOGUES | THE UPJOHN COMPANY (US) | 1986-10-01 | — | — | EP | disclosed |
| EP-0086611-B1 | 9-SUBSTITUTED CARBACYCLIN ANALOGUES | THE UPJOHN COMPANY (US) | 1986-05-21 | — | — | EP | disclosed |
| US-4588823-A | 9-substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1986-05-13 | — | — | US | disclosed |
| US-4585886-A | 9-Substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1986-04-29 | — | — | US | disclosed |
| US-4525586-A | Composition and process | THE UPJOHN COMPANY (US) | 1985-06-25 | — | — | US | disclosed |
| US-4490555-A | 9-Substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4487960-A | 9-Substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1984-12-11 | — | — | US | disclosed |
| US-4487961-A | ANTIULCER, ANTIASTHMA, ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1984-12-11 | — | — | US | disclosed |
| US-4420632-A | PROSTAGLANDINS; ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1983-12-13 | — | — | US | disclosed |
| US-4349689-A | Methano carbacyclin analogs | THE UPJOHN COMPANY (US) | 1982-09-14 | — | — | US | disclosed |
| US-4338457-A | Composition and process | THE UPJOHN COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4324889-A | 2,5-Inter-o-phenylene-3,4-dinor-6,9α-epoxy-6β-5-iodo-PGF1 amides | THE UPJOHN COMPANY (US) | 1982-04-13 | — | — | US | disclosed |
| US-4306075-A | Composition and process | THE UPJOHN COMPANY (US) | 1981-12-15 | — | — | US | disclosed |
| US-4306076-A | Inter-phenylene CBA compounds | THE UPJOHN COMPANY (US) | 1981-12-15 | — | — | US | disclosed |
| US-4289893-A | 2,5-Inter-O-phenylene-3,4-dinor-PGF2 compounds | THE UPJOHN COMPANY (US) | 1981-09-15 | — | — | US | disclosed |
| US-4281113-A | 2,5-Inter-o-phenylene-3,4-dinor-6,9α-epoxy-6.beta.-5-iodo-PGF1 compounds | THE UPJOHN COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4243592-A | THROMBOXANES; PROSTAGLANDINS; ANTIINFLAMMATORY AND BRONCHODILATOR AGENTS; ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4220796-A | 9-Deoxy-9-methylene-5,6-didehydro-PGF1 compounds | THE UPJOHN COMPANY (US) | 1980-09-02 | — | — | US | disclosed |
| US-4218378-A | 11a-Methano-TXA compounds | THE UPJOHN COMPANY (US) | 1980-08-19 | — | — | US | disclosed |