Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.90 |
| ▸ | FAAH | O00519 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | CNR1 | P21554 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30541869 | 0.95 | EPHX2 (1.00) | EPHX2FAAHCNR1 | |
| SCHEMBL28136625 | 0.95 | EPHX2 (1.00) | EPHX2FAAHCNR1 | |
| SCHEMBL28007018 | 0.95 | EPHX2 (1.00) | EPHX2FAAHCNR1 | |
| SCHEMBL30541868 | 0.95 | EPHX2 (1.00) | EPHX2FAAHCNR1 | |
| SCHEMBL19002581 | 0.92 | EPHX2 (0.80) | EPHX2FAAHALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL31659445 | 0.88 | EPHX2 (0.96) | EPHX2FAAHCNR1 | |
| SCHEMBL29639613 | 0.88 | EPHX2 (1.00) | EPHX2FAAHCNR1 | |
| SCHEMBL22558561 | 0.88 | EPHX2 (1.00) | EPHX2FAAHCNR1 | |
| SCHEMBL22558582 | 0.88 | EPHX2 (1.00) | EPHX2FAAHCNR1 | |
| SCHEMBL31659466 | 0.88 | EPHX2 (0.96) | EPHX2FAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454243-A2 | TETRAZOLE DERIVATIVES | Merck Serono SA (CH) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |