SCHEMBL9346366

SCHEMBL9346366

CCC(OC(=O)/C=C/C(=O)OC)[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.42
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42
GFPT1 Q06210 1/20 0.33
ATM Q13315 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9240616 0.93 HCAR2 (0.34) HCAR2ATM
SCHEMBL9240594 0.93 HCAR2 (0.34) HCAR2ATM
SCHEMBL9242313 0.87 HCAR2 (0.42) HCAR2KEAP1NFE2L2GFPT1ATM
SCHEMBL9238717 0.87 HCAR2 (0.46) HCAR2ATM
SCHEMBL10783950 0.87 HCAR2 (0.46) HCAR2ATM
SCHEMBL9242302 0.87 HCAR2 (0.42) HCAR2KEAP1NFE2L2GFPT1ATM
SCHEMBL9239070 0.87 HCAR2 (0.42) HCAR2KEAP1NFE2L2GFPT1ATM
SCHEMBL9243681 0.86 HCAR2 (0.44) HCAR2ATM
SCHEMBL9239924 0.83 HCAR2 (0.48) HCAR2KEAP1NFE2L2GFPT1ATM
SCHEMBL9239913 0.83 HCAR2 (0.48) HCAR2KEAP1NFE2L2GFPT1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0433046-B1 Polymer-type polymerization initiator TOMEI SANGYO KK (JP) 1994-08-10 EP disclosed
US-5206298-A GRAFT COPOLYMER, SOLUTION CONTAINING THE GRAFT COPOLYMER FOR TREATING CONTACT LENS, AND METHOD OF TREATING CONTACT LENS WITH THE SOLUTION AND MAKING HYDROPHILIC LENS SURFACE TOMEI SANGYO KABUSHIKI KAISHA (JP) 1993-04-27 US disclosed
US-5134213-A N-Vinyllactam-Monoperoxyfumarate Terpolymer TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-07-28 US disclosed
US-5082912-A For graft polymerization, surfactants TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-01-21 US disclosed
EP-0433046-A2 Polymer-type polymerization initiator Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-19 EP disclosed