Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 2/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010790 | 0.84 | HIF1A (0.43) | HIF1AMEN1KMT2ALMNABLM | |
| SCHEMBL8509316 | 0.84 | HIF1A (0.43) | HIF1AMEN1KMT2ALMNABLM | |
| SCHEMBL5182595 | 0.84 | HIF1A (0.43) | HIF1AMEN1KMT2ALMNABLM | |
| SCHEMBL15263324 | 0.84 | HIF1A (0.43) | HIF1AMEN1KMT2ALMNABLM | |
| SCHEMBL2636631 | 0.84 | HIF1A (0.43) | HIF1AMEN1KMT2ALMNABLM | |
| SCHEMBL1994115 | 0.84 | HIF1A (0.43) | HIF1AMEN1KMT2ALMNABLM | |
| SCHEMBL240028 | 0.84 | HIF1A (0.43) | HIF1AMEN1KMT2ALMNABLM | |
| SCHEMBL4436402 | 0.84 | HIF1A (0.43) | HIF1AMEN1KMT2ALMNABLM | |
| SCHEMBL9393256 | 0.84 | HIF1A (0.43) | HIF1AMEN1KMT2ALMNABLM | |
| Water SCHEMBL5144372 | 0.83 | HIF1A (0.42) | HIF1AMEN1KMT2ALMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353268-B1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS | NUCLEIC ACID RESEARCH INST (US) | 1994-08-10 | — | — | EP | claimed |
| EP-0353268-B1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS | NUCLEIC ACID RESEARCH INST (US) | 1994-08-10 | — | — | EP | disclosed |