Dimethylamine

Dimethylamine

SCHEMBL9347103

CC(O)CS(=O)(=O)O.CNC

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.37
GRIA1 P42261 3/20 0.36
TDP1 Q9NUW8 2/20 0.32
TSHR P16473 2/20 0.32
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GMNN O75496 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
PMP22 Q01453 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL28812089 1.00 SLC22A6 (0.37) SLC22A6GRIA1TDP1TSHRALDH1A1
Dimethylamine SCHEMBL28954501 0.97 SLC22A6 (0.36) SLC22A6GRIA1TDP1TSHRALDH1A1
SCHEMBL20898290 0.92
SCHEMBL549356 0.92
SCHEMBL9392015 0.89
SCHEMBL4299562 0.89
SCHEMBL19809590 0.89
SCHEMBL1138591 0.89
Water SCHEMBL19282561 0.89 SLC22A6 (0.40) SLC22A6GRIA1TDP1TSHRALDH1A1
SCHEMBL1138621 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0392865-B1 Extraction procedure UNILEVER PLC (GB) 1994-07-13 EP claimed
CN-111004835-B Stable formulations for luminescent detection of luciferases and nucleoside phosphates 普洛麦格公司 2023-12-29 CN disclosed
CN-102532321-B Novel antigen-binding polypeptides and its purposes AMBRX公司 2018-10-12 CN disclosed
CN-105039495-B A kind of 3 α HSD reagents and its preparation method and application 中生北控生物科技股份有限公司 2017-12-15 CN disclosed
CN-106443006-A Methods and compositions comprising non-natural amino acids AMBRX公司 2017-02-22 CN disclosed
CN-102603895-B Novel antigen-binding polypeptides and its purposes AMBRX公司 2016-09-28 CN disclosed
CN-103965300-A Biosynthetic Polypeptide Fusion Inhibitors AMBRX INC 2014-08-06 CN disclosed
CN-101489571-B Biosynthetic polypeptide fusion inhibitors AMBRX INC 2014-06-18 CN disclosed
CN-102603895-A Novel antigen-binding polypeptides and their uses AMBRX INC 2012-07-25 CN disclosed
CN-102532321-A Novel antigen-binding polypeptides and their uses AMBRX INC 2012-07-04 CN disclosed
CN-1968712-B Novel antigen binding polypeptides and uses thereof AMBRX INC 2012-05-16 CN disclosed
CN-1914223-B Modified human four-helix bundle polypeptides and uses thereof AMBRX INC 2012-02-29 CN disclosed
CN-102264697-A Biosynthetically generated pyrroline-carboxy-lysine and site-specific protein modification by chemical derivatization of pyrroline-carboxy-lysine and pyrrolysine residues 2011-11-30 CN disclosed
CN-101489571-A Biosynthetic polypeptide fusion inhibitors AMBRX INC (US) 2009-07-22 CN disclosed
CN-101454461-A Methods and compositions comprising unnatural amino acids AMBRX INC (US) 2009-06-10 CN disclosed
CN-101001866-A Modified human interferon polypeptides and their uses AMBRX INC (US) 2007-07-18 CN disclosed
CN-1968712-A Novel antigen binding polypeptides and uses thereof AMBRX INC (US) 2007-05-23 CN disclosed
CN-1942589-A Modified human growth hormone polypeptides and uses thereof AMBRX INC (US) 2007-04-04 CN disclosed
CN-1914223-A Modified human four-helix bundle polypeptides and uses thereof AMBRX INC (US) 2007-02-14 CN disclosed
CN-1568370-A treatment of central nervous system disorders with D-amino acid oxidase and D-aspartate oxidase antagonists GENSET SA (FR) 2005-01-19 CN disclosed