Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | TTR | P02766 | 1/20 | 0.68 |
| ▸ | PPOX | P50336 | 1/20 | 0.68 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactofen SCHEMBL8536001 | 0.91 | MEN1 (0.66) | TDP1MEN1KMT2ATTRPPOX | |
| Lactofen SCHEMBL30359837 | 0.91 | MEN1 (0.66) | TDP1MEN1KMT2ATTRPPOX | |
| Lactofen SCHEMBL30606811 | 0.91 | MEN1 (0.66) | TDP1MEN1KMT2ATTRPPOX | |
| Lactofen SCHEMBL29462400 | 0.91 | MEN1 (0.66) | TDP1MEN1KMT2ATTRPPOX | |
| Lactofen SCHEMBL9796531 | 0.91 | MEN1 (0.66) | TDP1MEN1KMT2ATTRPPOX | |
| Lactofen SCHEMBL39523 | 0.91 | MEN1 (0.66) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL2233678 | 0.91 | TDP1 (0.73) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9343367 | 0.90 | TDP1 (0.69) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11035747 | 0.90 | TDP1 (0.74) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10500814 | 0.90 | TDP1 (0.74) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304531-A | Preemergent, postemergent, controls weed growth 2-chloro-4-trifluoromethyl-3' (1-(carboethoxy) ethoxycarbonyl)-4-nitrodiphenyl ether | BASF CORPORATION | 1994-04-19 | — | — | US | disclosed |
| US-5214190-A | Nitrophenyl ether herbicides | JOHNSON WAYNE O (US) | 1993-05-25 | — | — | US | disclosed |
| US-5028732-A | Herbicidally active amino diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1991-07-02 | — | — | US | disclosed |
| US-4806682-A | Sulfonium salts of diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| US-4693742-A | Herbicidal hydroxyamino phosphonic acids and derivatives | ROHM AND HASS COMPANY (US) | 1987-09-15 | — | — | US | disclosed |
| US-4584014-A | PREEMERGENCE HERBICIDES;CORN, WHEAT AND OATS | ROHM AND HAAS COMPANY (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0020052-B1 | NOVEL SUBSTITUTED NITRODIPHENYL ETHERS, HERBICIDAL COMPOSITIONS CONTAINING THEM, PROCESSES FOR THE PREPARATION THEREOF AND THE USE THEREOF FOR COMBATING WEEDS | ROHM AND HAAS COMPANY (US) | 1983-07-20 | — | — | EP | disclosed |
| EP-0066217-A1 | Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, processes for the preparation thereof and the use thereof for combating weeds | ROHM AND HAAS COMPANY (US) | 1982-12-08 | — | — | EP | disclosed |
| EP-0020052-A1 | Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, processes for the preparation thereof and the use thereof for combating weeds | ROHM AND HAAS COMPANY (US) | 1980-12-10 | — | — | EP | disclosed |