Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TST | Q16762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9351158 | 0.96 | HSD17B10 (0.38) | HSD17B10ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9347699 | 0.96 | HSD17B10 (0.38) | HSD17B10ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9347830 | 0.87 | TSHR (0.34) | HSD17B10TSHR | |
| SCHEMBL9351600 | 0.85 | GRM2 (0.37) | KDM4EALDH1A1GRM2MAPTMGLL | |
| SCHEMBL23720068 | 0.81 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3ALDH1A1HIF1A | |
| SCHEMBL9347400 | 0.81 | GRM2 (0.39) | ALDH1A1HIF1AGRM2MAPT | |
| SCHEMBL9347436 | 0.77 | HTT (0.34) | TP53MAPTMGLLSMN1; SMN2 | |
| SCHEMBL9347714 | 0.77 | NPC1 (0.49) | LMNATP53ALDH1A1CYP3A4MAPT | |
| SCHEMBL9122543 | 0.75 | HSD17B10 (0.35) | HSD17B10ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL6056611 | 0.73 | ESR1 (0.41) | HSD17B10ESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438754-B1 | Optically active compound, intermediate therefor, process for producing the intermediate, and liquid-crystal composition | DAINIPPON INK & CHEMICALS (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5064564-A | Ferroelectric liquid crystal display | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1991-11-12 | — | — | US | disclosed |
| EP-0438754-A1 | Optically active compound, intermediate therefor, process for producing the intermediate, and liquid-crystal composition | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1991-07-31 | — | — | EP | disclosed |