Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347197 | 1.00 | FASN (0.36) | FASNTSHRHSD17B10GAAMAPT | |
| SCHEMBL9348423 | 1.00 | FASN (0.36) | FASNTSHRHSD17B10GAAMAPT | |
| SCHEMBL9348240 | 1.00 | FASN (0.36) | FASNTSHRHSD17B10GAAMAPT | |
| SCHEMBL9348334 | 1.00 | FASN (0.36) | FASNTSHRHSD17B10GAAMAPT | |
| SCHEMBL9351320 | 0.99 | FASN (0.37) | FASNTSHRHSD17B10ESR2HRH3 | |
| SCHEMBL9347678 | 0.96 | FASN (0.37) | FASNESR2HRH3 | |
| SCHEMBL9348274 | 0.91 | FASN (0.38) | FASNHRH3 | |
| SCHEMBL9631644 | 0.87 | TP53 (0.31) | — | |
| SCHEMBL9631707 | 0.87 | TP53 (0.31) | — | |
| SCHEMBL9631660 | 0.87 | TP53 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423926-B1 | Difluorobenzonitrile derivatives | CHISSO CORP (JP) | 1994-08-03 | — | — | EP | disclosed |
| EP-0423926-A1 | Difluorobenzonitrile derivatives | Chisso Corporation (JP) | 1991-04-24 | — | — | EP | disclosed |