Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.58 |
| ▸ | THRA | P10827 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 10/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605341 | 1.00 | PLK1 (0.58) | PLK1THRATHRBCA12CA1 | |
| SCHEMBL7604301 | 0.95 | NPC1 (0.52) | PLK1CA12CA1CA2CA9 | |
| SCHEMBL7607626 | 0.90 | ITGB1 (0.51) | PLK1KMT2A | |
| SCHEMBL7605317 | 0.84 | ITGB1 (0.50) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9558501 | 0.84 | CA12 (0.60) | PLK1THRATHRBCA12CA1 | |
| SCHEMBL9348775 | 0.82 | KMT2A (0.49) | PLK1THRBCA12CA1CA2 | |
| SCHEMBL9348635 | 0.81 | MAPT (0.47) | PLK1THRBEPHX1NPC1RAB9A | |
| SCHEMBL7604406 | 0.80 | NPC1 (0.52) | PLK1CA12CA1CA2CA9 | |
| SCHEMBL11352018 | 0.80 | CA12 (0.76) | THRATHRBCA12CA1CA2 | |
| SCHEMBL11361435 | 0.80 | CA12 (0.76) | THRATHRBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342958-A | Insecticides | SOLVAY DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1994-08-30 | — | — | US | disclosed |
| US-5245071-A | Insecticides | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1993-09-14 | — | — | US | disclosed |
| US-5142064-A | Larvicides has benzoyl or thiobenzoyl group | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-08-25 | — | — | US | disclosed |
| US-4920135-A | NONPHYTOTOXIC, INTERFERE WITH METAMORPHOSIS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-04-24 | — | — | US | disclosed |
| US-4833151-A | INTERFERES WITH METAMORPHOSES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1989-05-23 | — | — | US | disclosed |
| US-4607044-A | Insecticidal use of ureas and thioureas | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1986-08-19 | — | — | US | disclosed |
| US-4166124-A | IMIDAZOLE OR PYRIMIDINE RINGS | U.S. PHILIPS CORPORATION (US) | 1979-08-28 | — | — | US | disclosed |
| US-3989842-A | Certain substituted benzoyl urea insecticides | U.S. PHILIPS CORPORATION (US) | 1976-11-02 | — | — | US | disclosed |
| US-3933908-A | INSECTICIDE | U.S. PHILIPS CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |