Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 14/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9351877 | 0.99 | CYP1A2 (0.37) | CYP1A2OPRL1MAPK1MEN1GAA | |
| SCHEMBL9347694 | 0.96 | MEN1 (0.36) | CYP1A2OPRL1MEN1GAAKMT2A | |
| SCHEMBL9347889 | 0.94 | MAPT (0.36) | CYP1A2OPRL1MEN1GAAKMT2A | |
| SCHEMBL9351949 | 0.94 | MAPT (0.36) | CYP1A2OPRL1MEN1GAAKMT2A | |
| SCHEMBL9347881 | 0.94 | MEN1 (0.36) | CYP1A2OPRL1MEN1GAAKMT2A | |
| SCHEMBL9347767 | 0.93 | MAPT (0.37) | CYP1A2OPRL1MEN1GAAKMT2A | |
| SCHEMBL9347753 | 0.93 | MAPT (0.37) | CYP1A2OPRL1MEN1GAAKMT2A | |
| SCHEMBL9347877 | 0.91 | OPRL1 (0.36) | OPRL1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL9347740 | 0.90 | OPRL1 (0.37) | OPRL1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL9352141 | 0.88 | OPRL1 (0.36) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318721-A | Nematic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-07 | — | — | US | disclosed |
| US-4871469-A | TRIFLUOROTOLUENE DERIVATIVES | BESCRANKTER HAFTUNG (DE) | 1989-10-03 | — | — | US | disclosed |