Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9349702 | 1.00 | MAPT (0.41) | MAPTKDM4EMEN1NPC1HTT | |
| SCHEMBL9353373 | 0.89 | CYP19A1 (0.44) | MAPTMEN1KMT2ATDP1ESR1 | |
| SCHEMBL9353368 | 0.89 | CYP19A1 (0.44) | MAPTMEN1KMT2ATDP1ESR1 | |
| SCHEMBL9349694 | 0.85 | MAPT (0.44) | MAPTKDM4EMEN1NPC1RAB9A | |
| SCHEMBL9349686 | 0.85 | MAPT (0.44) | MAPTKDM4EMEN1NPC1RAB9A | |
| SCHEMBL9350506 | 0.83 | ESR1 (0.40) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9350508 | 0.83 | ESR1 (0.40) | MAPTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9349863 | 0.82 | ESR1 (0.40) | MAPTKDM4EMEN1HTTKMT2A | |
| SCHEMBL9349861 | 0.82 | ESR1 (0.40) | MAPTKDM4EMEN1HTTKMT2A | |
| SCHEMBL9350534 | 0.81 | CYP19A1 (0.48) | MAPTMEN1KMT2ATDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457184-B1 | Naphthol derivatives, method for their preparation and use therefor | BOEHRINGER MANNHEIM GMBH (DE) | 1994-08-17 | — | — | EP | disclosed |
| US-5194389-A | PH indicators | BOEHRINGER MANNHEIM GMBH (DE) | 1993-03-16 | — | — | US | disclosed |
| EP-0457184-A2 | Naphthol derivatives, method for their preparation and use therefor | Roche Diagnostics GmbH (DE) | 1991-11-21 | — | — | EP | disclosed |