Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9349775 | 1.00 | KDR (0.49) | KDRLMNAMPIESR1APAF1 | |
| SCHEMBL9350508 | 0.78 | ESR1 (0.40) | LMNAESR1MAPTKMT2ACYP19A1 | |
| SCHEMBL9350506 | 0.78 | ESR1 (0.40) | LMNAESR1MAPTKMT2ACYP19A1 | |
| SCHEMBL9353368 | 0.78 | CYP19A1 (0.44) | LMNAESR1MAPTKMT2ACYP19A1 | |
| SCHEMBL9353373 | 0.78 | CYP19A1 (0.44) | LMNAESR1MAPTKMT2ACYP19A1 | |
| SCHEMBL9349863 | 0.77 | ESR1 (0.40) | LMNAESR1APAF1MAPTNTSR1 | |
| SCHEMBL31462867 | 0.77 | CYP19A1 (0.39) | ESR1MAPTKMT2ACYP19A1THRA | |
| SCHEMBL9349700 | 0.77 | CYP19A1 (0.39) | ESR1MAPTKMT2ACYP19A1THRA | |
| SCHEMBL3171264 | 0.77 | CYP19A1 (0.39) | ESR1MAPTKMT2ACYP19A1THRA | |
| SCHEMBL9349703 | 0.77 | CYP19A1 (0.39) | ESR1MAPTKMT2ACYP19A1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457184-B1 | Naphthol derivatives, method for their preparation and use therefor | BOEHRINGER MANNHEIM GMBH (DE) | 1994-08-17 | — | — | EP | disclosed |
| US-5194389-A | PH indicators | BOEHRINGER MANNHEIM GMBH (DE) | 1993-03-16 | — | — | US | disclosed |
| EP-0457184-A2 | Naphthol derivatives, method for their preparation and use therefor | Roche Diagnostics GmbH (DE) | 1991-11-21 | — | — | EP | disclosed |