SCHEMBL9350324

SCHEMBL9350324

CCCCC(OC(=O)[C@@H]1CCC(=O)N1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.51
DAGLA Q9Y4D2 1/20 0.51
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.38
POLB P06746 1/20 0.35
TSHR P16473 1/20 0.35
DPP7 Q9UHL4 1/20 0.34
HDAC3 O15379 6/20 0.33
HDAC11 Q96DB2 6/20 0.33
HDAC6 Q9UBN7 6/20 0.33
HDAC1 Q13547 5/20 0.33
HDAC2 Q92769 5/20 0.33
HDAC10 Q969S8 5/20 0.33
HDAC8 Q9BY41 5/20 0.33
HDAC4 P56524 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
PTGES O14684 1/20 0.32
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9347473 0.96 CNR1 (0.55) CNR1DAGLALMNAGAAPOLB
SCHEMBL10603876 0.95 CNR1 (0.57) CNR1DAGLALMNAGAAPOLB
SCHEMBL9346795 0.95 CNR1 (0.57) CNR1DAGLALMNAGAAPOLB
SCHEMBL9221490 0.95 CNR1 (0.57) CNR1DAGLALMNAGAAPOLB
SCHEMBL9511146 0.95 CNR1 (0.57) CNR1DAGLALMNAGAAPOLB
SCHEMBL9221483 0.95 CNR1 (0.57) CNR1DAGLALMNAGAAPOLB
SCHEMBL9346460 0.92 CNR1 (0.47) CNR1DAGLALMNAGAAPOLB
SCHEMBL8749180 0.87 CNR1 (0.49) CNR1DAGLALMNAGAAPOLB
SCHEMBL9347494 0.86 CNR1 (0.44) CNR1DAGLALMNAGAAPOLB
SCHEMBL9347499 0.86 CNR1 (0.44) CNR1DAGLALMNAGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0342056-B1 Cosmetic composition UNILEVER PLC (GB) 1994-08-17 EP claimed
EP-0342054-B1 Cosmetic composition UNILEVER PLC (GB) 1993-11-03 EP claimed
EP-0176217-B1 PYROGLUTAMIC ACID ESTERS, THEIR SYNTHESIS AND USE IN TOPICAL PRODUCTS UNILEVER PLC (GB) 1989-06-07 EP claimed