Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.45 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9350598 | 1.00 | CTSC (0.57) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL1645427 | 0.90 | CTSC (0.58) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL9637178 | 0.86 | CTSC (0.54) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL9637180 | 0.86 | CTSC (0.54) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL4082518 | 0.86 | CTSC (0.42) | CTSCSLC7A5OPRD1OPRM1OPRK1 | |
| SCHEMBL2180720 | 0.84 | CTSC (0.61) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL8046880 | 0.84 | CTSC (0.61) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL8046881 | 0.84 | CTSC (0.61) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL9638023 | 0.82 | CTSC (0.50) | CTSCCYP3A4OPRD1OPRM1OPRK1 | |
| SCHEMBL9638027 | 0.82 | CTSC (0.50) | CTSCCYP3A4OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339217-B1 | Specific peptide bond cleavage by organic tertiary phosphines with nucleophilic side chains | CARTER WALLACE (US) | 1994-09-21 | — | — | EP | disclosed |
| US-4956467-A | CLEAVAGE OF PROTEINS AND SEQUENCE DETERMINATION | AMERICAN CYANAMID COMPANY (US) | 1990-09-11 | — | — | US | disclosed |
| EP-0339217-A2 | Specific peptide bond cleavage by organic tertiary phosphines with nucleophilic side chains | CARTER-WALLACE, INC. (US) | 1989-11-02 | — | — | EP | disclosed |