Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCD | Q05655 | 1/20 | 0.73 |
| ▸ | CETP | P11597 | 1/20 | 0.71 |
| ▸ | NT5E | P21589 | 3/20 | 0.70 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.68 |
| ▸ | RORC | P51449 | 2/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130038 | 1.00 | PRKCD (0.73) | PRKCDCETPNT5ENR1H4RORC | |
| SCHEMBL9128972 | 0.95 | CETP (0.74) | PRKCDCETPNT5ENR1H4RORC | |
| SCHEMBL9127646 | 0.94 | CETP (0.73) | PRKCDCETPNT5ENR1H4RORC | |
| SCHEMBL9129016 | 0.94 | CETP (0.72) | PRKCDCETPNT5ENR1H4RORC | |
| SCHEMBL9129033 | 0.94 | CETP (0.72) | PRKCDCETPNT5ENR1H4RORC | |
| SCHEMBL9573072 | 0.94 | CETP (0.72) | PRKCDCETPNT5ENR1H4RORC | |
| SCHEMBL9129009 | 0.94 | CETP (0.72) | PRKCDCETPNT5ENR1H4RORC | |
| SCHEMBL9128056 | 0.94 | CETP (0.72) | PRKCDCETPNT5ENR1H4RORC | |
| SCHEMBL9132841 | 0.94 | CETP (0.72) | PRKCDCETPNT5ENR1H4RORC | |
| SCHEMBL9350009 | 0.94 | CETP (0.72) | PRKCDCETPNT5ENR1H4RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613483-A1 | NEW LUPANE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1994-09-07 | — | — | EP | disclosed |
| WO-1993010142-A1 | NEW LUPANE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1993-05-27 | — | — | WO | disclosed |
| EP-0542622-A1 | New lupane derivatives, a process for their production and pharmaceutical compositions containing them | Aventis Pharma S.A. (FR) | 1993-05-19 | — | — | EP | disclosed |