Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.39 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9355184 | 0.99 | SPHK1 (0.36) | SPHK1TNNC1S1PR1S1PR3SGPL1 | |
| SCHEMBL9350916 | 0.98 | SPHK1 (0.39) | SPHK1TNNC1S1PR1S1PR3SGPL1 | |
| SCHEMBL9351394 | 0.98 | SPHK1 (0.39) | SPHK1TNNC1S1PR1S1PR3SGPL1 | |
| SCHEMBL9351655 | 0.98 | SPHK1 (0.39) | SPHK1TNNC1S1PR1S1PR3SGPL1 | |
| SCHEMBL9351562 | 0.96 | SPHK1 (0.36) | SPHK1TNNC1S1PR1S1PR3SGPL1 | |
| SCHEMBL9351298 | 0.95 | S1PR3 (0.38) | SPHK1TNNC1S1PR1S1PR3SGPL1 | |
| SCHEMBL9352102 | 0.95 | SPHK1 (0.39) | SPHK1TNNC1S1PR1S1PR3SGPL1 | |
| SCHEMBL9351083 | 0.95 | HRH3 (0.37) | SPHK1S1PR3CYP3A4ALDH1A1LMNA | |
| SCHEMBL9351121 | 0.94 | SPHK1 (0.36) | SPHK1TNNC1S1PR1S1PR3SGPL1 | |
| SCHEMBL9352431 | 0.94 | S1PR3 (0.36) | SPHK1TNNC1S1PR1S1PR3SGPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410756-B1 | Cyclohexenylethane compounds | CHISSO CORP (JP) | 1994-09-14 | — | — | EP | disclosed |
| US-5064565-A | Liquid crystals | CHISSO CORPORATION (JP) | 1991-11-12 | — | — | US | disclosed |
| EP-0410756-A1 | Cyclohexenylethane compounds | Chisso Corporation (JP) | 1991-01-30 | — | — | EP | disclosed |