Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9351278 | 1.00 | SPHK1 (0.49) | SPHK1CYP2C9MAPTSMN1; SMN2SPHK2 | |
| SCHEMBL11405906 | 1.00 | SPHK1 (0.49) | SPHK1CYP2C9MAPTSMN1; SMN2SPHK2 | |
| SCHEMBL11415518 | 0.99 | SPHK1 (0.51) | SPHK1CYP2C9MAPTSMN1; SMN2SPHK2 | |
| SCHEMBL11406446 | 0.99 | SPHK1 (0.51) | SPHK1CYP2C9MAPTSMN1; SMN2SPHK2 | |
| SCHEMBL11418397 | 0.99 | SPHK1 (0.51) | SPHK1CYP2C9MAPTSMN1; SMN2SPHK2 | |
| SCHEMBL11409215 | 0.99 | SPHK1 (0.51) | SPHK1CYP2C9MAPTSMN1; SMN2SPHK2 | |
| SCHEMBL11406635 | 0.99 | SPHK1 (0.51) | SPHK1CYP2C9MAPTSMN1; SMN2SPHK2 | |
| SCHEMBL11412025 | 0.99 | SPHK1 (0.51) | SPHK1CYP2C9MAPTSMN1; SMN2SPHK2 | |
| SCHEMBL11423006 | 0.99 | SPHK1 (0.51) | SPHK1CYP2C9MAPTSMN1; SMN2SPHK2 | |
| SCHEMBL11407291 | 0.99 | SPHK1 (0.51) | SPHK1CYP2C9MAPTSMN1; SMN2SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272580-B1 | Liquidcrystalline cyclohexylbenzene derivatives their manufacturing and novel nematic admixtures containing same | WOJSKOWA AKAD TECH (PL) | 1994-08-17 | — | — | EP | disclosed |
| EP-0272558-A2 | Process for glueing non-transparent carriers, and glueing systems for use therein | Henkel Kommanditgesellschaft auf Aktien (DE) | 1988-06-29 | — | — | EP | disclosed |