Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512292 | 1.00 | CYP1A2 (0.42) | CYP1A2PKMHTTLMNAMAPK1 | |
| SCHEMBL5364764 | 1.00 | CYP1A2 (0.42) | CYP1A2PKMHTTLMNAMAPK1 | |
| SCHEMBL19721902 | 1.00 | CYP1A2 (0.42) | CYP1A2PKMHTTLMNAMAPK1 | |
| SCHEMBL4804342 | 1.00 | CYP1A2 (0.42) | CYP1A2PKMHTTLMNAMAPK1 | |
| SCHEMBL10486301 | 0.98 | CYP1A2 (0.41) | CYP1A2PKMHTTLMNAMAPK1 | |
| SCHEMBL10485965 | 0.98 | CYP1A2 (0.41) | CYP1A2PKMHTTLMNAMAPK1 | |
| SCHEMBL10702793 | 0.98 | CYP1A2 (0.41) | CYP1A2PKMHTTLMNAMAPK1 | |
| SCHEMBL10708259 | 0.98 | CYP1A2 (0.41) | CYP1A2PKMHTTLMNAMAPK1 | |
| SCHEMBL19722348 | 0.98 | CYP1A2 (0.41) | CYP1A2PKMHTTLMNAMAPK1 | |
| SCHEMBL10486036 | 0.98 | CYP1A2 (0.41) | CYP1A2PKMHTTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318721-A | Nematic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-07 | — | — | US | disclosed |
| US-5188758-A | Electrooptical display element using a supertwist liquid crystal having specified elastic constants | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1993-02-23 | — | — | US | disclosed |
| US-5160451-A | Solids separated by liquid crystal composition, change in crystal phase causes change in frictional force | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-11-03 | — | — | US | disclosed |
| EP-0264435-B1 | SMECTIC LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1992-03-04 | — | — | EP | disclosed |
| US-4871469-A | TRIFLUOROTOLUENE DERIVATIVES | BESCRANKTER HAFTUNG (DE) | 1989-10-03 | — | — | US | disclosed |
| EP-0264435-A1 | SMECTIC LIQUID CRYSTAL PHASES. | MERCK PATENT GMBH (DE) | 1988-04-27 | — | — | EP | disclosed |
| EP-0258430-A1 | NEMATIC LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1988-03-09 | — | — | EP | disclosed |
| EP-0132553-B1 | BICYCLOHEXYLES | MERCK PATENT GmbH (DE) | 1988-02-10 | — | — | EP | disclosed |
| WO-1987006602-A1 | SMECTIC LIQUID CRYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-11-05 | — | — | WO | disclosed |
| WO-1987005316-A1 | NEMATIC LIQUID CRYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-09-11 | — | — | WO | disclosed |